Issue August 2005

Research Update - Clinical Trials in our Sights

Research at Leicester

Action for Tinnitus Research has supported research at the University of Leicester since 2002. This facility is beginning to make important inroads into the causes and potential treatments for tinnitus. One such study is the investigation of drugs that already successfully treat epilepsy and pain. Action for Tinnitus Research would like to continue to support this research and raise enough funds to start Clinical Trials.
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The 'Science'

There is evidence that in conditions such as pain and epilepsy, affected nerves exhibit changes in the way they generate bioelectrical signals. This is what makes up nerve impulses (1). It is possible that similar changes may affect the auditory nerve and the parts of the brain that deal with hearing.
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Clinical Trials on the Horizon

This work builds on the research evidence for effective treatments for tinnitus. The next step is to gain approval for a study to go ahead. This is done via an independent review. The Clinical Trial aims to distinguish which tinnitus patients respond to treatment and which do not. Those who respond positively will then be followed up for an extended period to regularly monitor the group.

We need your continued support to ensure these Clinical Trials can go ahead. Please support in whatever way you can.
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Reference 1. Moller AR. (2000). Similarities between severe tinnitus and chronic pain. Journal of the American Academy of Audiology. 11, 115-124.